Ethylene oxide an gane shi azaman faffadan bakan da kuma maganin kashe gaseous mai matukar tasiri, tukuna yana haifar da babbar illa ga lafiyar ɗan adam, yana nuna matakan guba sama da na chloroform da carbon tetrachloride.
Da farko, ta nufa hanyar numfashi, haifar da bayyanar cututtuka kamar tashin zuciya, amai, gudawa, da zafi, tare da tsarin juyayi na tsakiya. A lokuta masu tsanani, yana iya ƙaru zuwa damuwa na numfashi da edema na huhu.