IU.S. Environmental Protection Agency (EPA) parizvino iri kuita ongororo yekubatana pakati pebutadiene negomarara.
Uyezve, EPA yakagadzira hurongwa hwekugadzirisa kuparadzirwa kwebenzene, chinozivikanwa secarcinogen. Iyo agency inotsigira iyo yakakura data iripo inoratidza izvozvo butadiene, pamwe chete neyavo synthetic rabha yekugadzira maitiro, zvakanyanya njodzi hutano hwevanhu.